Platform

Thousands of compounds. One signaling map.

Rationally designed β₂-adrenergic ligands, profiled across eight signaling pathways. Explore 28 key compounds from our Cell publication, grouped into five clusters by multi-pathway efficacy.

of rationally designed compounds
in the Atrogi platform
granted patents
protecting the platform
key ligands
profiled in our Cell paper
signaling readouts
per compound
3D explorer

The signaling landscape.

Each point is a ligand, placed by its efficacy on three pathways you choose. Color marks its cluster. Select a point to open its full profile.

Compound profiles

28 ligands. Five signaling classes.

Filter by cluster or rank by pathway. Efficacy is normalized to isoprenaline, the reference full agonist (100%).

Cluster
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Showing 28 of 28 compoundsOrdered by cluster
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