Compound A Strong GRK2-biasedGlucose uptake 92% GRK2 69% cAMP 15% β-arrestin2 0%
Compound B Strong GRK2-biasedGlucose uptake 82% GRK2 58% cAMP 13% β-arrestin2 0%
Compound C Strong GRK2-biasedGlucose uptake 82% GRK2 37% cAMP 19% β-arrestin2 0%
Compound D Strong GRK2-biasedGlucose uptake 105% GRK2 27% cAMP 14% β-arrestin2 0%
Compound E Strong GRK2-biasedGlucose uptake 118% GRK2 42% cAMP 17% β-arrestin2 0%
Compound F Strong GRK2-biasedGlucose uptake 111% GRK2 60% cAMP 19% β-arrestin2 0%
bamethane GRK2-selectiveGlucose uptake 89% GRK2 56% cAMP 7% β-arrestin2 0%
Compound G GRK2-selectiveGlucose uptake 95% GRK2 43% cAMP 17% β-arrestin2 0%
Compound H GRK2-selectiveGlucose uptake 103% GRK2 58% cAMP 7% β-arrestin2 0%
Compound I GRK2-selectiveGlucose uptake 96% GRK2 48% cAMP 10% β-arrestin2 0%
Compound J GRK2-selectiveGlucose uptake 101% GRK2 47% cAMP 14% β-arrestin2 0%
Compound K Partial GRK2-biasedGlucose uptake 92% GRK2 41% cAMP 42% β-arrestin2 0%
Compound L Partial GRK2-biasedGlucose uptake 106% GRK2 45% cAMP 36% β-arrestin2 0%
Compound M Partial GRK2-biasedGlucose uptake 65% GRK2 43% cAMP 43% β-arrestin2 0%
Compound N Partial GRK2-biasedGlucose uptake 95% GRK2 73% cAMP 53% β-arrestin2 0%
Compound O Partial GRK2-biasedGlucose uptake 78% GRK2 68% cAMP 43% β-arrestin2 0%
BRL-37344 Moderate Gs-biasedGlucose uptake 85% GRK2 39% cAMP 24% β-arrestin2 0%
Compound P Moderate Gs-biasedGlucose uptake 124% GRK2 60% cAMP 51% β-arrestin2 0%
Compound Q Moderate Gs-biasedGlucose uptake 96% GRK2 61% cAMP 47% β-arrestin2 0%
Compound R Moderate Gs-biasedGlucose uptake 110% GRK2 47% cAMP 35% β-arrestin2 0%
Compound S Moderate Gs-biasedGlucose uptake 92% GRK2 44% cAMP 49% β-arrestin2 0%
salbutamol Moderate Gs-biasedGlucose uptake 121% GRK2 51% cAMP 104% β-arrestin2 14%
clenbuterol Moderate Gs-biasedGlucose uptake 103% GRK2 49% cAMP 93% β-arrestin2 0%
higenamine Moderate Gs-biasedGlucose uptake 98% GRK2 79% cAMP 113% β-arrestin2 0%
adrenaline Balanced full agonistGlucose uptake 116% GRK2 105% cAMP 117% β-arrestin2 124%
isoprenaline Balanced full agonistGlucose uptake 100% GRK2 100% cAMP 100% β-arrestin2 100%
colterol Balanced full agonistGlucose uptake 111% GRK2 110% cAMP 103% β-arrestin2 112%
noradrenaline Balanced full agonistGlucose uptake 105% GRK2 91% cAMP 119% β-arrestin2 69%